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COMPASS, a program within the Biostatistics Program in the Public Health Sciences Division of the Fred Hutchinson Cancer Research Center (FHCRC), provides full-spectrum operational support for research and has been directing multi-center studies in public health research for over 30 years. Currently, COMPASS coordinates the large multi-center health initiatives: the Early Detection Research Network (EDRN) Data Management and Coordinating Center, the Population-based Research to Optimize the Screening Process (PROSPR) Coordination Center, the Translational Liver Cancer (TLC) Consortium Data Management and Coordinating Center, and the New-Onset Diabetes (NOD) Cohort. Additionally, COMPASS continues to maintain the Carotene and Retinol Efficacy Trial (CARET) specimen repository. COMPASS previously coordinated the Transdisciplinary Research on Energetics and Cancer (TREC) Coordination Center, the Olestra Post-Marketing Surveillance Study (OPMSS), provided services to the Asian Cancer Consortium (ACC), and has been involved in numerous smaller scale projects. More details about each project can be found under Research & Collaboration.

As part of these initiatives, COMPASS provides overall network coordination, site monitoring, web-based data entry and specimen tracking systems, reports, data harmonization, Common Data Element development, and statistical services.