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The New-Onset Diabetes (NOD) cohort is jointly funded by NCI and NIDDK and is part of the Consortium for the study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). The CPDPC sub-contracted NOD coordination to the EDRN-DMCC. The goals of NOD are to prospectively assemble a cohort of subjects >50 and <85 years of age with New-Onset Diabetes (NOD), called the NOD Cohort, in order to:

  • Estimate the probability of pancreatic ductal adenocarcinoma (PDAC) in the NOD Cohort,
  • Establish a biobank of clinically annotated biospecimens including a reference set of biospecimens from pre-symptomatic PDAC and control new-onset type 2 diabetes mellitus (DM) subjects,
  • Facilitate validation of emerging tests for identifying NOD subjects at high risk for having PDAC using the reference set, and
  • Provide a platform for development of an interventional protocol for early detection of sporadic PDAC NOD subjects.